BDBM364440 2-fluoro-N-[6-(hydroxymethyl)-2- phenyl-2H-indazol-3-yl]-5-(1H- pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9862707, Example 14

SMILES OCc1ccc2c(NC(=O)c3cc(-c4cc[nH]n4)c(cc3F)C(F)(F)F)n(nc2c1)-c1ccccc1

InChI Key InChIKey=KUWWQOJJZDEENF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364440   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM364440(2-fluoro-N-[6-(hydroxymethyl)-2- phenyl-2H-indazol...)
Affinity DataIC50:  1.20nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent