BDBM364542 (4bR,6S,8aS,9R)-6-amino-11- (cyclopropylmethyl)-3-methoxy- 5,6,7,8,9,10- hexahydro-9,4b-(epiminoethano)- 8a,6-(epoxymethano)phenanthren-15-one::US9862726, Compound 3

SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC5(N)CC[C@@]34OC5=O)c2c1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 364542   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM364542(US9862726, Compound 3 | (4bR,6S,8aS,9R)-6-amino-11...)
Affinity DataKi:  248nMAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM364542(US9862726, Compound 3 | (4bR,6S,8aS,9R)-6-amino-11...)
Affinity DataKi:  1.33E+3nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent