BDBM364558 N-((4bR,6S,8aS,9R)-11- (cyclopropylmethyl)- 3-methoxy-5,6,7,8,9,10-hexahydro-9,4b- (epiminoethano)-8a,6- (epoxymethano)phenanthren-6-yl)-3,3,3- trifluoropropanamide::US9862726, Compound 23

SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC5(CC[C@@]34OC5)NC(=O)CC(F)(F)F)c2c1

InChI Key InChIKey=ZIXLRXOGMVFKHJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 364558   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM364558(US9862726, Compound 23 | N-((4bR,6S,8aS,9R)-11- (c...)
Affinity DataKi:  0.660nMAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM364558(US9862726, Compound 23 | N-((4bR,6S,8aS,9R)-11- (c...)
Affinity DataKi:  136nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent