BDBM365245 US9868720, No. 143::[2-((2R,5R)-2,5-Dimethyl- pyrrolidin-1-yl)-6- piperidin-4-yl-pyrimidin- 4-yl]-(4-trifluoromethyl- pyridin-2-yl)-amine

SMILES C[C@@H]1CC[C@@H](C)N1c1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCNCC1

InChI Key InChIKey=HXNPWEIJZMDUOY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365245   

LigandPNGBDBM365245(US9868720, No. 143 | [2-((2R,5R)-2,5-Dimethyl- pyr...)
Affinity DataKi:  10.4nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
US Patent