BDBM365298 US9868720, No. 404::{2-(3,3-Difluoro-pyrrolidin- 1-yl)-6-[1-(1H-pyrazol- 4-ylmethyl)-pyrrolidin- 3-yl]-pyrimidin-4- yl}-(4-trifluoromethyl- pyridin-2-yl)-amine

SMILES FC1(F)CCN(c2nc(Nc3cc(C(F)(F)F)ccn3)cc(C3CCN(Cc4cn[nH]c4)C3)n2)C1

InChI Key InChIKey=CPOPQLDAPPSWBB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365298   

LigandChemical structure of BindingDB Monomer ID 365298BDBM365298(US9868720, No. 404 | {2-(3,3-Difluoro-pyrrolidin- ...)
Affinity DataKi:  4.92nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
US Patent