BDBM365369 US10633373, Example 74::US10669265, Example 74::US9868726, Example 74::methyl 6-amino-5-[4-({[2- fluoro-5- (trifluoromethyl)phenyl]carbamoyl} amino)phenyl]pyridine- 3-carboxylate

SMILES COC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1

InChI Key InChIKey=OIUSMJPCEZOFLD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365369   

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM365369(US10633373, Example 74 | US10669265, Example 74 | ...)
Affinity DataIC50:  7nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM365369(US10633373, Example 74 | US10669265, Example 74 | ...)
Affinity DataIC50:  7nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM365369(US10633373, Example 74 | US10669265, Example 74 | ...)
Affinity DataIC50:  7nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent