BDBM365741 4-Amino-6-{(3R,4S)-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile::US9867826, Compound 40
SMILES Nc1ncnc(N2CC[C@H]([C@@H](F)C2)c2nc(cn2CCN2CCC2)-c2ccc(F)c(c2)C(F)(F)F)c1C#N
InChI Key InChIKey=FVBJUIPMIDIVCZ-UZLBHIALSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 365741
Affinity DataIC50: 5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair