BDBM366186 US9873693, Compound 109::US9873693, Compound 264

SMILES COc1ccnc(NCCC#CCNC(=O)c2cccn(Cc3ccc(F)c(F)c3)c2=O)n1

InChI Key InChIKey=MUPKDDDPMOIBME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 366186   

Target3-phosphoinositide-dependent protein kinase 1 [51-360](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366186(US9873693, Compound 264 | US9873693, Compound 109)
Affinity DataIC50: 500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1 [51-360](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366186(US9873693, Compound 264 | US9873693, Compound 109)
Affinity DataIC50: 500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent