BDBM366190 US9873693, Compound 113::US9873693, Compound 274

SMILES Fc1ccc(Cn2cccc(C(=O)NCCOc3ccc4[nH]c(=O)[nH]c4c3)c2=O)cc1F

InChI Key InChIKey=SQTIRPOTBHMSMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 366190   

Target3-phosphoinositide-dependent protein kinase 1 [51-360](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366190(US9873693, Compound 274 | US9873693, Compound 113)
Affinity DataIC50: 500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1 [51-360](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366190(US9873693, Compound 274 | US9873693, Compound 113)
Affinity DataIC50: 500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent