BDBM367213 6-benzoyl-2-oxo-N-(4-phenyl- butyl)-1,3-benzoxazole-3- carboxamide::US10226452, Example 37

SMILES O=C(NCCCCc1ccccc1)n1c2ccc(cc2oc1=O)C(=O)c1ccccc1

InChI Key InChIKey=OVYCTSIDMKYFCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367213   

TargetAcid ceramidase(Human)
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367213(6-benzoyl-2-oxo-N-(4-phenyl- butyl)-1,3-benzoxazol...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human acid ceramidase expressed in HEK293 cells using N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)-4-(2-oxochromen-7-yl)-oxybutyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367213(6-benzoyl-2-oxo-N-(4-phenyl- butyl)-1,3-benzoxazol...)
Affinity DataIC50: 29nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent