BDBM367219 2-oxo-N-(3-phenylpropyl)- 1,3-benzoxazole-3- carboxamide::US10226452, Example 43

SMILES O=C(NCCCc1ccccc1)n1c2ccccc2oc1=O

InChI Key InChIKey=QOXAWFVYIBPGFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367219   

TargetAcid ceramidase(Human)
University of California

US Patent
LigandPNGBDBM367219(2-oxo-N-(3-phenylpropyl)- 1,3-benzoxazole-3- carbo...)
Affinity DataIC50: 55nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAcid ceramidase(Human)
University of California

US Patent
LigandPNGBDBM367219(2-oxo-N-(3-phenylpropyl)- 1,3-benzoxazole-3- carbo...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human acid ceramidase expressed in HEK293 cells using N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)-4-(2-oxochromen-7-yl)-oxybutyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed