BDBM368308 US10227338, Example 95

SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F

InChI Key InChIKey=DCWUXXOCLXFRRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368308   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368308(US10227338, Example 95)
Affinity DataIC50:  8.20E+3nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368308(US10227338, Example 95)
Affinity DataIC50:  30nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent