BDBM368311 US10227338, Example 121::US10227338, Example 98

SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1

InChI Key InChIKey=XTFYQLJKBAXFAQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 368311   

TargetSodium channel protein type 9 subunit alpha(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368311(US10227338, Example 121 | US10227338, Example 98)
Affinity DataIC50:  40nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium channel protein type 5 subunit alpha(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368311(US10227338, Example 121 | US10227338, Example 98)
Affinity DataIC50: >1.00E+4nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium channel protein type 9 subunit alpha(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368311(US10227338, Example 121 | US10227338, Example 98)
Affinity DataIC50:  60nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent