BDBM368487 N-(1H-pyrazolo[4,3-b] pyridin-3-yl)-1- (tetrahydropyran-2- ylmethoxy)isoquinolin-6- amine::US10227343, Example 22::US10968227, Compound 56

SMILES C(Oc1nccc2cc(Nc3n[nH]c4cccnc34)ccc12)C1CCCCO1

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368487   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368487(N-(1H-pyrazolo[4,3-b] pyridin-3-yl)-1- (tetrahydro...)
Affinity DataEC50:  78.8nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368487(N-(1H-pyrazolo[4,3-b] pyridin-3-yl)-1- (tetrahydro...)
Affinity DataEC50:  79nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent