BDBM368491 1-ethoxy-N-(1H-pyrazolo [4,3-b]pyridin-3-yl) isoquinolin-6-amine::US10227343, Example 26

SMILES CCOc1nccc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key InChIKey=HWOFLRQXVOYMFW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368491   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368491(1-ethoxy-N-(1H-pyrazolo [4,3-b]pyridin-3-yl) isoqu...)
Affinity DataEC50:  33nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent