BDBM368500 4-fluoro-N-(1H-pyrazolo [4,3-b]pyridin-3-yl)-1- pyrazol-1-yl-isoquinolin- 6-amine::US10227343, Example 33

SMILES Fc1cnc(-n2cccn2)c2ccc(Nc3n[nH]c4cccnc34)cc12

InChI Key InChIKey=GMOUJPATGKBHRQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368500   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368500(4-fluoro-N-(1H-pyrazolo [4,3-b]pyridin-3-yl)-1- py...)
Affinity DataEC50:  102nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent