BDBM368604 US10227350, Compound 25

SMILES NC(=O)c1cc(cc2n(c(nc12)C1CC1)-c1ccnc2c(Cl)ccc(F)c12)-c1ccnc(N)c1F

InChI Key InChIKey=KQGYYJVVRFKDES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368604   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM368604(US10227350, Compound 25)
Affinity DataIC50: 6nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent