BDBM368996 N-(2-Oxoindolin-5-yl)furan-2-carboxamide::US12528797, Example 2

SMILES O=C1Cc2cc(NC(=O)c3ccco3)ccc2N1

InChI Key InChIKey=AEVVBZLHFSKGEW-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368996   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 368996BDBM368996(N-(2-Oxoindolin-5-yl)furan-2-carboxamide | US12528...)
Affinity DataKd:  7nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent