BDBM369022 (3S,4R,5R)-1-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperidine-3,4,5-triol::US12528773, Example 2

SMILES O[C@H]1[C@H](O)CN(C[C@H]2CC[C@@H](C(F)(F)F)CC2)C[C@@H]1O

InChI Key InChIKey=QRSDASXAGDFAHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369022   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369022BDBM369022((3S,4R,5R)-1-(((1s,4S)-4-(trifluoromethyl)cyclohex...)
Affinity DataIC50: 100nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 100 mM citric acid, 200 mM disodium phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent