BDBM369140 (3S,4R,5R)-1-(((R)-1-(5- isopropylthiazol-2-yl)piperidin-3- yl)methyl)piperidine-3,4,5-triol::US12528773, Example 32

SMILES CC(C)c1cnc(N2CCC[C@H](CN3C[C@@H](O)[C@H](O)[C@@H](O)C3)C2)s1

InChI Key InChIKey=ZBNKIOVFAHZZQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369140   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369140BDBM369140((3S,4R,5R)-1-(((R)-1-(5- isopropylthiazol-2-yl)pip...)
Affinity DataIC50: 100nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 100 mM citric acid, 200 mM disodium phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent