BDBM369185 (3S,4r,5R)-1-([1,1'-biphenyl]-4-ylmethyl)piperidine-3,4,5-triol::US12528773, Example 202

SMILES O[C@H]1[C@H](O)CN(Cc2ccc(-c3ccccc3)cc2)C[C@@H]1O

InChI Key InChIKey=WENSQDKPNNBQSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369185   

TargetNon-lysosomal glucosylceramidase(Rat)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369185BDBM369185((3S,4r,5R)-1-([1,1'-biphenyl]-4-ylmethyl)piperidin...)
Affinity DataIC50: 100nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 100 mM citric acid, 200 mM disodium phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent