BDBM369191 2-Isopropyl-N-methyl-1-(2-oxoindolin-5-yl)benzimidazole-5-carboxamide::US12528797, Example 5

SMILES CNC(=O)c1ccc2c(c1)nc(C(C)C)n2-c1ccc2c(c1)CC(=O)N2

InChI Key InChIKey=RHPKLISJUMXXGP-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369191   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369191BDBM369191(2-Isopropyl-N-methyl-1-(2-oxoindolin-5-yl)benzimid...)
Affinity DataKd:  3nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent