BDBM369206 5-(Indoline-1-carbonyl)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one::US12528797, Example 20

SMILES O=C1Cc2cc(C(=O)N3CCc4ccccc43)cnc2N1

InChI Key InChIKey=GHYOQXIMNSDMIB-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369206   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369206BDBM369206(5-(Indoline-1-carbonyl)-1,3-dihydropyrrolo[2,3-b]p...)
Affinity DataKd:  13nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent