BDBM369207 3,3-Difluoro-5-(2-isopropylbenzimidazol-1-yl)indolin-2-one::US12528797, Example 21

SMILES CC(C)c1nc2ccccc2n1-c1ccc2c(c1)C(F)(F)C(=O)N2

InChI Key InChIKey=LKLDZQPYAMXBNF-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369207   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369207BDBM369207(3,3-Difluoro-5-(2-isopropylbenzimidazol-1-yl)indol...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent