BDBM369208 6-(4-Hydroxyisoindoline-2-carbonyl)-3H-1,3-benzoxazol-2-one::US12528797, Example 22

SMILES O=C(c1ccc2[nH]c(=O)oc2c1)N1Cc2cccc(O)c2C1

InChI Key InChIKey=MPQMYKZHPVCIIY-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369208   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369208BDBM369208(6-(4-Hydroxyisoindoline-2-carbonyl)-3H-1,3-benzoxa...)
Affinity DataKd:  2nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent