BDBM369209 6-(4-Nitroisoindoline-2-carbonyl)-3H-1,3-benzoxazol-2-one::US12528797, Example 23

SMILES O=C(c2ccc1[nH]c(=O)oc1c2)N4Cc3cccc([N+](=O)[O-])c3C4

InChI Key InChIKey=ZSJZTDWGVWPMQS-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369209   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369209BDBM369209(6-(4-Nitroisoindoline-2-carbonyl)-3H-1,3-benzoxazo...)
Affinity DataKd:  14nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent