BDBM369270 US12528814, Example 54

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)CCOCCC(=O)N2CCN(c3nnc(-c4cnc(-c5ccc6cc(C#N)cnn56)cc4NC(C)C)s3)CC2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1

InChI Key InChIKey=DTAOWVLMQWTKIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369270   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369270BDBM369270(US12528814, Example 54)
Affinity DataIC50: 0.600nMAssay Description:The binding capacities of certain bifunctional compounds of Formula (I) were determined using the CisBio HTRF KinEASE STK S1 Kit (#62ST1PEB, contains...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369270BDBM369270(US12528814, Example 54)
Affinity DataIC50: 0.600nMAssay Description:The binding capacities of certain bifunctional compounds of Formula (I) were determined using the CisBio HTRF KinEASE STK S1 Kit (#62ST1PEB, contains...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent