BDBM369724 US10233160, Compound 14::US9981925, Compound 14
SMILES NC(=O)c1cccc2c(N[C@H](CN3CCC3)c3ccc(Cl)c(c3)C(F)(F)F)nnnc12
InChI Key InChIKey=RNQGOVIVNIRUOZ-MRXNPFEDSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 369724
Affinity DataIC50: <25nMAssay Description:p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...More data for this Ligand-Target Pair