BDBM370465 1-cyclohexyl-2-(8-fluoro-5H-imidazo[5,1- a]isoindol-5-yl)ethanol;::US10233190, Example 1376
SMILES OC(CC1c2ccc(F)cc2-c2cncn12)C1CCCCC1
InChI Key InChIKey=GZLGDNBVPZDDHN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 370465
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair