BDBM370527 (4-fluorophenyl)(4-(1-hydroxy-2-(5H- imidazo[5,1-a]isoindol-5-yl)ethyl)piperidin-1- yl)methanone::US10233190, Example 1450

SMILES OC(CC1c2ccccc2-c2cncn12)C1CCN(CC1)C(=O)c1ccc(F)cc1

InChI Key InChIKey=SBGDHJQZWJCENG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370527   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM370527((4-fluorophenyl)(4-(1-hydroxy-2-(5H- imidazo[5,1-a...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM370527((4-fluorophenyl)(4-(1-hydroxy-2-(5H- imidazo[5,1-a...)
Affinity DataIC50:  550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent