BDBM370536 US10233190, Example 1469::tert-butyl 4-((S)-1-hydroxy-2-((R)-5H- imidazo[5,1-a]isoindol-5-yl)ethyl)piperidine-1- carboxylate

SMILES CC(C)(C)OC(=O)N1CCC(CC1)[C@@H](O)C[C@@H]1c2ccccc2-c2cncn12

InChI Key InChIKey=QYRWUEOAQAHUBN-QUCCMNQESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370536   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM370536(US10233190, Example 1469 | tert-butyl 4-((S)-1-hyd...)
Affinity DataIC50:  550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent