BDBM370541 2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(pyridin-3- yl)ethanol::US10233190, Example 1474

SMILES OC(CC1c2ccccc2-c2cncn12)c1cccnc1

InChI Key InChIKey=JNVJGLYGJXLWMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370541   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM370541(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(pyridin-3- y...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM370541(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(pyridin-3- y...)
Affinity DataIC50:  550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent