BDBM370781 US10239835, Example 00333

SMILES Oc1ccc(C(O)CN2C[C@H]3C[C@H](Oc4ccc(F)cc4F)C[C@H]3C2)nc1

InChI Key InChIKey=AKEUOXXGTLYITE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370781   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Cadent Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 370781BDBM370781(US10239835, Example 00333)
Affinity DataIC50: 6.81nMAssay Description:Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent