BDBM370867 N-ethyl-4-fluoro-N-{2-[5-(1- hydroxy-1-methylethyl)pyridin-2- yl]ethyl}-2-(2H-1,2,3-triazol-2- yl)benzamide::US10239838, Example 61

SMILES CCN(CCc1ccc(cn1)C(C)(C)O)C(=O)c1ccc(F)cc1-n1nccn1

InChI Key InChIKey=XTRIJUNORZKAMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370867   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370867(US10239838, Example 61 | N-ethyl-4-fluoro-N-{2-[5-...)
Affinity DataIC50: 26nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370867(US10239838, Example 61 | N-ethyl-4-fluoro-N-{2-[5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent