BDBM371876 US10239870, Example 89::US10239870, Example 94

SMILES Cn1c(SCCCN2CC[C@]3(CC3c3ccc(cc3)C(F)(F)F)C2)nnc1C1CCCCC1

InChI Key InChIKey=CTRVTEOXKBMCKO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371876   

TargetD(3) dopamine receptor(Rat)
Indivior

US Patent
LigandPNGBDBM371876(US10239870, Example 94 | US10239870, Example 89)
Affinity DataKi:  0.186nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Indivior

US Patent
LigandPNGBDBM371876(US10239870, Example 94 | US10239870, Example 89)
Affinity DataKi:  0.832nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent