BDBM371932 3-[(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(1H-indazole-5-carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::US10239876, Example 33::US10435407, Example 33

SMILES O=C(N1CCC2(CC1)N(CN(Cc1nc(no1)C1CC1)C2=O)c1ccccc1)c1ccc2[nH]ncc2c1

InChI Key InChIKey=SCNJPRUXBGWNTB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371932   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM371932(3-[(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(...)
Affinity DataIC50:  13.8nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD(1A) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM371932(3-[(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(...)
Affinity DataIC50:  13.8nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent