BDBM372017 (rac, cis)-3-[2-(2-Benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)-2-oxoethyl]-8-(1H-indazole-5-carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::US10239876, Example 58::US10435407, Example 58

SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)N1C[C@@H]2CN(Cc3ccccc3)C[C@@H]2C1

InChI Key InChIKey=ADWGVRCUXBWAOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372017   

TargetD(1A) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 372017BDBM372017((rac, cis)-3-[2-(2-Benzyl-1,3,3a,4,6,6a-hexahydrop...)
Affinity DataIC50: 807nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 372017BDBM372017((rac, cis)-3-[2-(2-Benzyl-1,3,3a,4,6,6a-hexahydrop...)
Affinity DataIC50: 807nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent