BDBM372081 2-(8-(3-Amino-1H-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)-N-(2,2,2-trifluoroethyl)acetamide::US10239876, Example 104::US10435407, Example 104

SMILES Nc1n[nH]c2ccc(cc12)C(=O)N1CCC2(CC1)N(CN(CC(=O)NCC(F)(F)F)C2=O)c1ccccc1

InChI Key InChIKey=HYVLWRNCEBMMRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372081   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372081(2-(8-(3-Amino-1H-indazole-5-carbonyl)-4-oxo-1-phen...)
Affinity DataIC50:  21nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372081(2-(8-(3-Amino-1H-indazole-5-carbonyl)-4-oxo-1-phen...)
Affinity DataIC50:  21nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent