BDBM372125 (S)- or (R)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-(2-(trifluoromethyl)morpholino)ethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::US10239876, Example 148::US10435407, Example 148

SMILES FC(F)(F)[C@H]1CN(CCO1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372125   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM372125((S)- or (R)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-...)
Affinity DataIC50:  18.1nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(1A) dopamine receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM372125((S)- or (R)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-...)
Affinity DataIC50:  18.1nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent