BDBM372166 N-(3- morpholinopropyl)- 6-(o-tolyl)-5H- pyrrolo[3,2- d]pyrimidin-2- amine::US10239881, Example A19::US10875863, Example A19

SMILES Cc1ccccc1-c1cc2nc(NCCCN3CCOCC3)ncc2[nH]1

InChI Key InChIKey=UCMHPIFFDFPXCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372166   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372166(US10239881, Example A19 | N-(3- morpholinopropyl)-...)
Affinity DataIC50: 500nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network

US Patent
LigandPNGBDBM372166(US10239881, Example A19 | N-(3- morpholinopropyl)-...)
Affinity DataIC50: 500nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent