BDBM372168 (1r,4)-4-((6- (o-tolyl)- 5H-pyrrolo[3,2- d]pyrimidin-2- yl)amino) cyclohexanol::US10239881, Example A21::US10239881, Example A22::US10875863, Example A22
SMILES Cc1ccccc1-c1cc2nc(N[C@@H]3CC[C@H](O)CC3)ncc2[nH]1
InChI Key InChIKey=RAWDDZNDVWIRKN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 372168
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network
US Patent
University Health Network
US Patent
Affinity DataIC50: 300nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network
US Patent
University Health Network
US Patent
Affinity DataIC50: 300nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network
US Patent
University Health Network
US Patent
Affinity DataIC50: 500nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University Health Network
US Patent
University Health Network
US Patent
Affinity DataIC50: 500nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair