BDBM372303 3-(3-chloro-2-fluoro-6-((2,2,7-trifluorobenzo[d][1,3]dioxol-4-yl)oxy)-4-trifluoromethyl-benzamido)pyridine 1-oxide::US20260022100, Compound I-11

SMILES O=C(Nc1ccc[n+]([O-])c1)c1c(Oc2ccc(F)c3c2OC(F)(F)O3)cc(C(F)(F)F)c(Cl)c1F

InChI Key InChIKey=KANDTJBDPLGYLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372303   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372303BDBM372303(3-(3-chloro-2-fluoro-6-((2,2,7-trifluorobenzo[d][1...)
Affinity DataIC50: 0.640nMAssay Description:Reagents were purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. The final concentrations of the test compounds were a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent