BDBM372304 3-(3-chloro-2-fluoro-6-((3,3,6,7-tetrafluoro-2,3- dihydro-1H-inden-4-yl)oxy)-4- (trifluoromethyl)benzamide)pyridine 1-oxide::US20260022100, Compound I-14

SMILES O=C(Nc1ccc[n+]([O-])c1)c1c(Oc2cc(F)c(F)c3c2C(F)(F)CC3)cc(C(F)(F)F)c(Cl)c1F

InChI Key InChIKey=JAVZHNRZOZTUCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372304   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372304BDBM372304(3-(3-chloro-2-fluoro-6-((3,3,6,7-tetrafluoro-2,3- ...)
Affinity DataIC50: 10nMAssay Description:Reagents were purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. The final concentrations of the test compounds were a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent