BDBM372310 3-(5-chloro-2-((2,2,7-trifluorobenzo[d][1,3]dioxol-4- yl)oxy)-4-(trifluoromethyl)benzamido)pyridine 1-oxide::US20260022100, Compound I-23

SMILES O=C(Nc1ccc[n+]([O-])c1)c1cc(Cl)c(C(F)(F)F)cc1Oc1ccc(F)c2c1OC(F)(F)O2

InChI Key InChIKey=JAYKMUISLLAUIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372310   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372310BDBM372310(3-(5-chloro-2-((2,2,7-trifluorobenzo[d][1,3]dioxol...)
Affinity DataIC50: 2.90nMAssay Description:Reagents were purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. The final concentrations of the test compounds were a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent