BDBM372311 5-(4,5-dichloro-2-(2-(methoxy-d3)-4-(trifluoromethoxy)phenoxy)benzamido)pyrimidine 1-oxide::US20260022100, Compound I-24

SMILES [2H]C([2H])([2H])Oc1cc(OC(F)(F)F)ccc1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1cnc[n+]([O-])c1

InChI Key InChIKey=ODVPYMKONUDKSA-FIBGUPNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372311   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372311BDBM372311(5-(4,5-dichloro-2-(2-(methoxy-d3)-4-(trifluorometh...)
Affinity DataIC50: 2.20nMAssay Description:Reagents were purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. The final concentrations of the test compounds were a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent