BDBM372312 5-(3-Chloro-6-(4-(difluoromethoxy)phenoxy)-2-fluoro-4-(trifluoromethyl)benzamido)pyrimidine 1-oxide::US20260022100, Compound I-25

SMILES O=C(Nc1cnc[n+]([O-])c1)c1c(Oc2ccc(OC(F)F)cc2)cc(C(F)(F)F)c(Cl)c1F

InChI Key InChIKey=BRUAHTDQGVJQIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372312   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372312BDBM372312(5-(3-Chloro-6-(4-(difluoromethoxy)phenoxy)-2-fluor...)
Affinity DataIC50: 2.90nMAssay Description:Reagents were purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. The final concentrations of the test compounds were a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent