BDBM372313 5-(3-chloro-6-(4,5-difluoro-2-(methoxy-d3)phenoxy)-2-fluoro-4-(trifluoromethyl)benzamido)pyrimidine 1-oxide::US20260022100, Compound I-28

SMILES [2H]C([2H])([2H])Oc1cc(F)c(F)cc1OC1=CC(C(F)(F)F)C(Cl)C(F)=C1C(=O)NC1C=NC=[N+]([O-])C1

InChI Key InChIKey=AGKVFKLYMTVVPT-FIBGUPNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372313   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372313BDBM372313(5-(3-chloro-6-(4,5-difluoro-2-(methoxy-d3)phenoxy)...)
Affinity DataIC50: 1.30nMAssay Description:Reagents were purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. The final concentrations of the test compounds were a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent