BDBM372314 5-(5-chloro-2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)pyrimidine 1-oxide::US20260022100, Compound I-31

SMILES Cc1cc(F)ccc1Oc1cc(C(F)(F)F)c(Cl)cc1C(=O)Nc1cnc[n+]([O-])c1

InChI Key InChIKey=KUYXINAOPZYFIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372314   

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372314BDBM372314(5-(5-chloro-2-(4-fluoro-2-methylphenoxy)-4-(triflu...)
Affinity DataIC50: 9.75nMAssay Description:Reagents were purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. The final concentrations of the test compounds were a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent