BDBM373377 6-((6-((1R,4R)-2-oxa-5- azabicyclo[2.2.1]heptane-5- carbonyl)-5-methylpyrrolo[1,2- b]pyridazin-4-yl)oxy)-7-fluoro- N,2-dimethylbenzofuran-3- carboxamide::US20260022125, Example 7.2

SMILES CNC(=O)n5c(C)cc4cc(Oc2ccnn3cc(C(=O)N1C[C@@](C)(O)[C@H]1C)c(C)c23)ccc45

InChI Key InChIKey=OIVDDAGJICCRKR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373377   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 373377BDBM373377(6-((6-((1R,4R)-2-oxa-5- azabicyclo[2.2.1]heptane-5...)
Affinity DataEC50:  1nMAssay Description:The enzymatic activity of hVEGFR2 was measured using the TR-FRET based Ulight assay (Revvity) which measures phosphorylation of a fluorescently tagge...More data for this Ligand-Target Pair
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Date in BDB:
6/3/2026
Entry Details
US Patent