BDBM373476 6-({6-[3- (acetylamino)azetidine-1- carbonyl]-5-methylpyrrolo[1,2- b]pyridazin-4-yl}oxy)-N- (cyclopropylmethyl)-2-methyl- 1-benzofuran-3-carboxamide::US20260022125, Example 7.79

SMILES CC(=O)NC1CN(C(=O)c2cn3nccc(Oc4ccc5c(C(=O)NCC6CC6)c(C)oc5c4)c3c2C)C1

InChI Key InChIKey=WIGSVKZJXSOIKS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373476   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 373476BDBM373476(6-({6-[3- (acetylamino)azetidine-1- carbonyl]-5-me...)
Affinity DataEC50:  1.60nMAssay Description:The enzymatic activity of hVEGFR2 was measured using the TR-FRET based Ulight assay (Revvity) which measures phosphorylation of a fluorescently tagge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent